All products Antibodies SMAD2 Antibody

SMAD2 Antibody

Catalog Number：OM291653

  • Immunohistochemistry staining of SMAD2 in placenta tissue using SMAD2 Antibody.

Product Profile

Product Name SMAD2 Antibody
Antibody Type Primary Antibodies
Product description 
SMAD2 is an intracellular protein belonging to the Dwarfin (DWA/B)/SMAD family. SMAD2 associates with SMAD4 for translocation to nucleus. It acts as an intracellular mediator of TGFbeta family of cytokines and activin type 1 receptor (ACVR1C). Hence it regulates multiple cellular processes like cell growth, proliferation, differentiation, and apoptosis and also cooperates with transcription factors to regulate expression of defined genes. Apart from playing an important role in TGFbeta1-induced CTGF expression they also act as markers of EMT in human PTECs. It also acts as an integrator of multiple signals in the regulation of NOS3 expression. It is ubiquitously expressed in most of the tissues and is responsible for colorectal, hepatocellular, lung and breast carcinomas as well as cervical cancer.
Immunogen 
SMAD2 antibody was raised against amino acids 234 - 249 of SMAD2 (Human).

Key Feature

Clonality Polyclonal
Host Species Rabbit
Tested Applications

IHCWB
SMAD2 antibody can be used in ELISA, Western Blot starting at 1:500 - 1:1000, and immunohistochemistry starting at 5 μg/mL.:
Species Reactivity

BatBovineChickenDogGibbonHamsterHorseHumanMonkeyMouseOrangutanRabbitRatXenopus
Concentration 1 mg/ml
Purification Protein G

Target Information

Gene Symbol SMAD2
Alternative Names
SMAD2
HMAD-2
HSMAD2
JV18-1
Mad protein homolog smad2
MADR2
MADH2
SMAD 2
MAD homolog 2
Mad-related protein 2
JV18
Mother against DPP homolog 2
Mothers against DPP homolog 2
Sma- and Mad-related protein 2
SMAD family member 2
Tissue Specificity The SMAD2 amino acid sequence used as immunogen is 100% homologous in human (isoform 1:467 amino acids; isoform 2:437 amino acids), mouse, rat, horse, cow, chicken and Xenopus.

Database Links

Entrez Gene 4087
Protein Accession Q15796

Application

  • Application

    Immunohistochemistry staining of SMAD2 in placenta tissue using SMAD2 Antibody.

Application Notes
SMAD2 antibody can be used in ELISA, Western Blot starting at 1:500 - 1:1000, and immunohistochemistry starting at 5 μg/mL.:

Additional Information

Form Liquid
Storage Instructions SMAD2 antibody can be stored short term 4 ˚C. For long term storage aliquot and store at -20 ˚C. As with all antibodies avoid freeze/thaw cycles.
Storage Buffer PBS, 0.05% BSA, 0.05% sodium azide
Note: The product is for research use only,not for use in diagnostic or therapeutic procedures.

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  • Catalog Number: OM291653
  • Price: $336.00
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  • Lead time: 4~6 Week

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