Smad2 (phospho Thr220) Antibody

Product Profile

Product Name	Smad2 (phospho Thr220) Antibody
Antibody Type	Primary Antibodies
Product description	Transcriptional modulator activated by TGF-beta and activin type 1 receptor kinase. SMAD2 is a receptor-regulated SMAD (R-SMAD). May act as a tumor suppressor in colorectal carcinoma.1) Sang Gyun Kim et al. (2004) Mol Biol Cell. February; 15 (2): 420–434. Rebecca A. Randall et al. (2004) Mol Cell Biol. February; 24 (3): 1106–1121. Kimberly A Brown et al. (2004) Breast Cancer Res. ; 6 (3): R215–R231.
Immunogen	Smad2 (Phospho-Thr220) antibody was raised against a peptide sequence around phosphorylation site of threonine 220 (P-E-T (p) -P-P) derived from Human Smad2.

Key Feature

Clonality	Polyclonal
Host Species	Rabbit
Tested Applications	WB
	Western Blot: 1:500~1:1000:
Species Reactivity	HumanMouseRat
Concentration	1 mg/ml
Purification	Affinity purified

Target Information

Gene Symbol	SMAD2
Alternative Names	JV18 MADH2 MADR2 JV18-1 hMAD-2 hSMAD2 ERBB ERBB1 HER1 Mad-related protein 2 Mothers against DPP homolog 2
Molecular Weight(MW)	60 kDa
Tissue Specificity	This antibody detects endogenous level of Smad2 only when phosphorylated at threonine 220.

Database Links

Entrez Gene	4087
Protein Accession	NP_001003652.1

Application

Application Notes	Western Blot: 1:500~1:1000:

Additional Information

Form	Liquid
Storage Instructions	Store antibody at -20˚C for up to one year.
Storage Buffer	Antibody supplied in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.

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• Data sheet for OM291650