Application
Western blot analysis of ZNF224 expression in Jurkat whole cell lysate (A) and HL-60 nuclear extract (B).| Product Name | ZNF224 Antibody (G-16) |
|---|---|
| Antibody Type | Primary Antibodies |
| Modification Notes | Zinc-finger proteins contain DNA-binding domains and have a wide variety of functions, most of which encompass some form of transcriptional activation or repression. The majority of zinc-finger proteins contain a Krüppel-type DNA binding domain and a KRAB domain, which is thought to interact with KAP1, thereby recruiting histone modifying proteins. Zinc finger protein 224 (ZNF224), also known as BMZF2, KOX22, ZNF233, ZNF255 or ZNF27, is a 707 amino acid member of the Krüppel C2H2-type zinc-finger protein family. Localized to the nucleus, ZNF224 contains eighteen C2H2-type zinc fingers and one KRAB domain through which it is thought to be involved in DNA-binding and transcriptional regulation. Expressed mainly in fatal tissues, ZNF224 interacts with and interferes with the transactivation of Wilms tumor 1 (WT1). |
| Clonality | Polyclonal |
|---|---|
| Isotype | IgG |
| Host Species | Rabbit |
| Tested Applications | WBIPELISA |
| recommended for detection of ZNF224 of human origin by WB, IP and ELISA | |
| Species Reactivity | HumanMouseRat |
| Concentration | 1mg/ml |
| Purification | Affinity purified |
| Alternative Names | raised against ZNF224 of human origin |
|---|---|
| Tissue Specificity | raised against ZNF224 of human origin |
| Entrez Gene | 7767 |
|---|
Application
Western blot analysis of ZNF224 expression in Jurkat whole cell lysate (A) and HL-60 nuclear extract (B).| Application Notes | recommended for detection of ZNF224 of human origin by WB, IP and ELISA |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | For short-term storage, store at 4° C. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles. |
| Storage Buffer | phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
Data sheet for OM204198