| Product Name | CD3 epsilon antibody |
|---|---|
| Antibody Type | Primary Antibodies |
| Product description | Mouse monoclonal antibody [3F43] to CD3 epsilonThe protein encoded by this gene is the CD3-epsilon polypeptide, which together with CD3-gamma, -delta and -zeta, and the T-cell receptor alpha/beta and gamma/delta heterodimers, forms the T-cell receptor-CD3 complex. This complex plays an important role in coupling antigen recognition to several intracellular signal-transduction pathways. The genes encoding the epsilon, gamma and delta polypeptides are located in the same cluster on chromosome 11. The epsilon polypeptide plays an essential role in T-cell development. Defects in this gene cause immunodeficiency. This gene has also been linked to a susceptibility to type I diabetes in women. [provided by RefSeq, Jul 2008] |
| Immunogen | Human recombinant CD3ε |
| Clonality | Monoclonal |
|---|---|
| Isotype | IgG1 |
| Clone Number | 3F43 |
| Host Species | Mouse |
| Tested Applications | FACSIHCUnknown |
| IHC(1:50-100)|FC(1:50-100)|T cell activation: |
|
| Species Reactivity | Human |
| Concentration | 1mg/ml |
| Purification | Affinity purified |
| Gene Synonyms | CD3E T3E TCRE CD3e molecule epsilon (CD3-TCR complex) |
|---|---|
| Target | CD3 epsilon |
| Tissue Specificity | This antibody was selected for its ability to detect human CD3e |
| Application Notes | IHC(1:50-100)|FC(1:50-100)|T cell activation: |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | Keep as concentrated solution. Aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles. |
| Storage Buffer | PBS |
