| Product Name | DcR1 antibody |
|---|---|
| Antibody Type | Primary Antibodies |
| Product description | Mouse monoclonal antibody [4H10] to DcR1The protein encoded by this gene is a member of the TNF-receptor superfamily. This receptor contains an extracellular TRAIL-binding domain and a transmembrane domain, but no cytoplasmic death domain. This receptor is not capable of inducing apoptosis, and is thought to function as an antagonistic receptor that protects cells from TRAIL-induced apoptosis. This gene was found to be a p53-regulated DNA damage-inducible gene. The expression of this gene was detected in many normal tissues but not in most cancer cell lines, which may explain the specific sensitivity of cancer cells to the apoptosis-inducing activity of TRAIL. [provided by RefSeq, Jul 2008] |
| Immunogen | Human recombinant DcR1 EC domain |
| Clonality | Monoclonal |
|---|---|
| Isotype | IgG1 |
| Clone Number | 4H10 |
| Host Species | Mouse |
| Tested Applications | IHCWB |
| WB(1:500-1000)|IHC (paraffin)(1:20-100): |
|
| Species Reactivity | Human |
| Concentration | 1mg/ml |
| Purification | Affinity purified |
| Gene Synonyms | CD263 DCR1-TNFR TRAIL-R3 DCR1 TRID tumor necrosis factor receptor superfamily member 10c decoy without an intracellular domain LIT TRAILR3 |
|---|---|
| Target | DcR1 |
| Tissue Specificity | This antibody was selected for its ability to detect human DcR1. |
| Application Notes | WB(1:500-1000)|IHC (paraffin)(1:20-100): |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | Keep as concentrated solution. Aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles. |
| Storage Buffer | PBS |
